Formulations Chemist III

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Glaukos is an equal opportunity employer and makes employment decisions on the basis of merit. Glaukos participates in E-Verify. The Company policy prohibits discrimination based on race, color, creed, gender, gender identity, religion, marital status, registered domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, genetic information, sexual orientation, covered veteran status, or any other consideration made unlawful by applicable federal, state, or local laws. It also prohibits unlawful discrimination based on the perception that anyone has any of those characteristics, or is associated with a person who has or is perceived as having any of those characteristics.

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Glaukos is an ophthalmic medical technology company focused on the development and commercialization of breakthrough products and procedures designed to transform the treatment of glaucoma, one of the world's leading causes of blindness. We have pioneered Micro-Invasive Glaucoma Surgery, or MIGS, to revolutionize the traditional glaucoma treatment and management paradigm. We launched the iStent, our first MIGS device, in the United States in July 2012 and we are leveraging our platform technology to build a comprehensive and proprietary portfolio of micro-scale injectable therapies designed to address the complete range of glaucoma disease states and progression. We believe the iStent is the smallest medical device ever approved by the Food and Drug Administration, or FDA, measuring 1.0 mm long and 0.33 mm wide. 

Position Overview:

The Chemist III, within the Drug Delivery Innovation, Protein Delivery group, will be based in San Clemente, California, this role will be responsible for the designs and conducts experiments leading to the characterization and development of protein drug delivery systems for the eye.  The position is laboratory based and the hands-on generation of reliable and reproducible data is critical.  The position requires the use of sound scientific methods with a high degree precision and accuracy.  A working knowledge of a wide range of analytical methodologies is required including HPLC, FTIR, UV-Vis, GPC, and GC. The formulation and compounding of ophthalmic protein and small molecule drug delivery systems will also be required. Strong written communication and the ability to work on multiple projects is also essential to the position.


Responsibilities:  

Drug Delivery System Characterization:

Designs and executes experiments and analytical methodologies leading to the development and characterization of drug delivery systems.  Assesses the stability, physicochemical properties and in vitro drug release rates of drug delivery systems.  Using hypothesis based approaches and experimental design methodologies formulates new drug delivery systems under the supervision of the manager.

Cross-Functional Project Execution:

Work cross-functionally within Applied Research and across the organization including Product Engineering to evaluate the performance of protein and small molecule drug delivery systems.  This would include assisting in the planning and execution of in vivo studies as well as the relevant device development as they relate to drug delivery system development.

Documentation and Reporting:

Generates technical reports, memos and validation reports to document research, results and conclusions.  Writes SOPs and guidance's as necessary.  Assists in the writing of patents based on discoveries.

Laboratory Support:

Responsible for the sourcing, maintenance and operation of laboratory equipment.  Participates in and ensures laboratory safety at all times.  Keeps an up-to-date and accurate laboratory notebook and records of work. 

Professional:

Stays current with the scientific literature on drug delivery, analytical techniques, protein delivery and analysis and pharmaceutical sciences.

Work Experience:   

·         Scientist/ Chemist III: Minimum of 5 years of experience in medical device or pharmaceutical research or advanced degree with requisite experience. Prior research in another field may be substituted if there is sufficient evidence of laboratory skill developed in that field.

·         Staff Chemist: Minimum of 8 years of experience in medical device or pharmaceutical research. Prior research in another field may be substituted if there is sufficient evidence of laboratory skill developed in that field.

  • Experienced researcher with proven record of hypothesis driven research, experimental design and problem solving leading to the development of pharmaceutical formulations
  • Experience in formulating and characterizing pharmaceutical drug delivery systems including concepts of mass transfer, polymer degradation and in vitro drug release.  Experience in protein formulation development and characterization is a plus.
  • Pharmaceutical science knowledge including solubility, pKa, stability, and physical characterization.  Knowledge of polymer chemistry is a plus.
  • Glaukos is a small, entrepreneurial company where each person is responsible for many different functions.  We are looking for a person who will flourish in this kind of environment—a hands-on, self-motivated individual who can develop new chemistries and analytical methods with minimal direction.
  • A versatile hands-on bench chemist, an individual contributor

·         A wide range of analytical method knowledge such as HPLC, GC, FTIR, UV-Vis, NMR and GPC is required

·         Good oral and written skills

Education:

PHD or MS in Pharmaceutics, Physical Chemistry, Chemical Engineering, Polymer Chemistry or related discipline. An advanced degree is preferred, but would consider BS with the right proven track record.  PhD with 0 - 2 years Industrial experience or MS with 2 - 4 years Industrial experience.  BS with minimum of 5 years relevant experience.

We offer competitive salary (based on experience), bonus eligibility, medical/dental/vision, life insurance, stock options, 401(k) Employer Match, 3 weeks paid time off, 13 company paid holidays, Employee Stock Purchase Program and 2 additional paid days off to volunteer in our community, plus the opportunity to work for a company that is pioneering a new glaucoma treatment class. Check out our profile on The Muse to get an inside look at our company culture: https://www.themuse.com/companies/glaukoscorporation

Glaukos has been recognized by the Orange County Business Journal as one of the best companies to work for in in Orange County, check out page 8 at http://www.cbjonline.com/a1ocbj/lists/List-2017-OC_Best-Places-to-Work.pdf 

Glaukos Corporation is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.

 

 

 

Location: Applied Research in San Clemente, CA
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Apply at: https://glaukos.synchr-recruit.com/job/88284/formulations-chemist-iii